SMIRKS Practice


Write SMIRKS for each of the transforms described below.


  1. Produce hydronium ions (H30+) and chloride ions from water and hydrochloric acid.
  2.  
  3. Produce aliphatic primary amines (*CCN) from aliphatic nitriles (*CC#N) .
  4.  
  5. Produce aliphatic aldehydes (*CC=O) and ammonium ions ([NH4+]) from aliphatic nitriles (*CC#N) using DIBAL ([AlH](CC(C)C)CC(C)C , di-isobutyl aluminum hydride) and aqueous acid([OH3+]).
  6.  
  7. Write a generic SMIRKS that will transform both cyclic and non-cyclic anhydrides into
  8.