Geoff Skillman
UCSF, 513 Parnassus Ave., Box 0446, San Francisco, CA 94122


In order to make structure-based combinatorial design an efficient process, it is critical to have an organic chemist familiar with the pertinent reactions select the potential starting materials for a combinatorial library. To fascilitate this process, we have developed a "chemist friendly" cgi-based merlin client. This program allows the chemist to identify essential and contradictory functional groups and chemical properties using push-buttons and pull down menu selections from the comfort of their own internet browser. The cgi program then parses the chemist's selections into a series of merlin searches and carries them out, returning the results to the chemist's browser for further inspection.

Sample Page

MUG '98 Presentation

Demo with Maybridge98 database

Download from UCSF

Daylight Chemical Information Systems, Inc.