Revised Hydrophobic Parameter, ?? From Alkane/Octanol Comparison
log P(O/W) = 3.67 V - 0.40 ?* + 0.00 ?? - 3.00 ?? + 0.24
log P(A/O) = 0.95 V - 0.34 ?* - 3.20 ?? - 2.00 ?? - 0.22
log P(A/O) values are new datatype in Masterfile (Over 1300)
Measured values in any alkane considered, but.n-alkane is standard, ...
...so positive cyclohexane values adjusted to n-alkane scale (x 0.92†)
Alkane values averaged after judgement of reliability
?? values adjusted for difference in McGowan volume
†Coefficient applies, for example, to n-alkanols, and seems contrary to ‘like dissolves like’; i.e., 1-heptanol favored by cyclohexane compared to n-heptane