- Methodology for extracting and analysing rings
- Comprehensive Daylight database of rings
- Web interface and links to other databases
- Application to medchem projects for geometricand bioisosteres
- Enhancement with stereo isomers, tautomers, multiple ring conformations
- Continued capture and use of knowledge in drug discovery
- Full paper:
- Lewell et al, J Med Chem, 2003, 46, 3257-74, “Drug Rings Database with Web Interface. A Tool for Identifying Alternative Chemical Rings in Lead Discovery Programs”.